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Toplam kayıt 51, listelenen: 41-50
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer’xxs and Parkinson’xxs diseases
(Academic Press, 2019)
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update ...
Chapter 33 - Methods to study the effect of solution variables on the conformational dynamics of intrinsically disordered proteins
(Elsevier Academic Press, 2022)
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Intrinsically disordered proteins and proteins with intrinsically disordered regions in neurodegenerative diseases
(Elsevier BV., 2022)
Many diferent intrinsically disordered proteins and proteins with intrinsically disordered regions are associated with neurodegenerative diseases. These types of proteins including amyloid-β, tau, α-synuclein, CHCHD2, ...
Intrinsically disordered synthetic polymers in biomedical applications
(Polymers, 2023)
In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They ...
Covalent dimerization of interleukin-like epithelial-to-mesenchymal transition (EMT) inducer (ILEI) facilitates EMT, invasion, and late aspects of metastasis
(2017)
The interleukin-like epithelial-to-mesenchymal transition (EMT) inducer(ILEI)/FAM3C is a member of the highly homologous FAM3 family andis essential for EMT and metastasis formation. It is upregulated in severalcancers, ...
Paving the way for synthetic intrinsically disordered polymers for soft robotics
(2023)
Nature is full of examples of processes that, through evolution, have been perfected over
the ages to effectively use matter and sustain life. Here, we present our strategies for designing intrinsically disordered smart ...
Structures of MERS-CoV macro domain in aqueous solution with dynamics: Impacts of parallel tempering simulation techniques and\n CHARMM36m\n and\n AMBER99SB\n force field parameters
(Wiley, 2021)
A novel virus, severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), causing
coronavirus disease 2019 (COVID-19) worldwide appeared in 2019. Detailed scientific
knowledge of the members of the Coronaviridae family, ...
Insights into the structural properties of SARS-CoV-2 main protease
(Elsevier BV, 2022)
SARS-CoV-2 is the infectious agent responsible for the coronavirus disease since 2019, which is the viral pneumonia pandemic worldwide. The structural knowledge on SARS-CoV-2 is rather limited. These limitations are ...
The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10
(2023)
The mitochondria are responsible for producing energy within the cell, and in mitochondrial myop-athy, there is a defect in the energy production process. The CHCHD10 gene codes for a protein calledcoiled-coil-helix-coil ...
Effects of the Jokela type of spinal muscular atrophy-relatedG66V mutation on the structural ensemble characteristics ofCHCHD10
(2023)
The G66V pathological variant of the coiled-coil-helix-coiled-coil-helix domain-containing protein 10 (CHCHD10), mitochondrial, plays a role in Jokela type spinalmuscular atrophy. The wild-type and G66V mutant-type CHCHD10 ...