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Identification of deleterious non-synonymous single nucleotide polymorphisms in the mRNA decay activator ZFP36L2
(2024)More than 4,000 single nucleotide polymorphisms (SNP) variants have been identified in the human ZFP36L2 gene, however only a few have been studied in the context of protein function. The tandem zinc finger domain of ... -
İskelet kaslarındaki kuvvet üretim mekanizmasının Huxley tipi kas modelleriyle incelenmesi
(2021)Hareketin gerçekleştirilmesinde birincil rol oynayan ve lokomotor sistem bileşenlerinden olan iskelet kasları, kasılma esnasında çeşitli biyokimyasal ve mekanik süreçler sonucunda kuvvet üretirler. Kas kuvvetlerinin ... -
Does intramedullary elastic nail augmentation increase resistance to bending stress in plate fixation of long bones? A biomechanical study on lamb cadaveric femurs
(2023)The aim of this study was to evaluate the bending strength of plate-screw fixation augmented with titanium elastic nails (TENs) in a simple long bone fracture model using lamb cadaver femurs. Materials and methods: A total ... -
A tale of captopril detection based on an electrochemical mip sensör
(2024)Amaç: Bu çalışmada antihipertansif bir ilaç olan Kaptoprilin tespitine yönelik moleküler baskılama yöntemi ile hazırlanmış sensörler kullanılarak voltametrik bir yöntem geliştirilmesi amaçlanmıştır. Gereç ve Yöntem: Moleküler ... -
Kritik madenlerin kullanıldığı ürünler ülke ekonomisine katkı sunar
(2024)Geleceğin katma değerli ekonomisinde belirleyici unsurlar arasında sadece lityum, grafit, kobalt ve nikel değil bor, nadir toprak elementleri, bakır, altın, gümüş, manganez, titanyum, demir, silisyum ve alüminyum içeren ... -
Specific features of epitope-MIPs and whole-protein MIPs as illustrated for AFP and RBD of SARS-CoV-2
(2024)Molecularly imprinted polymer (MIP) nanofilms for alpha-fetoprotein (AFP) and the receptor binding domain (RBD) of the spike protein of SARS-CoV-2 using either a peptide (epitope-MIP) or the whole protein (protein-MIP) as ... -
Effect of various carbon electrodes on MIP-Based sensing proteins using poly(Scopoletin): A case study of ferritin
(2024)Sensitivity in the sub-nanomolar concentration region is required to determine important protein biomarkers, e.g., ferritin. As a prerequisite for high sensitivity, in this paper, the affinity of the functional monomer ... -
Chapter 33 - Kinematics, kinetics, and forces of the knee joint during walking
(Elsevier-Academic Press, 2024)Motion analysis is a valuable tool to monitor the kinematics and kinetics of body parts quantitatively and the decision-making process in clinical implementations. In gait analysis systems, temporospatial parameters, joint ... -
Evaluation of mandibular condyle position in Class III patients after bimaxillary orthognathic surgery: A cone-beam computed tomography study
(2024)This retrospective study evaluated the mandibular condyle position before and after bimaxillary orthognathic surgery performed with the mandibular condyle positioned manually in patients with mandibular prognathism using ... -
Evaluation of treatment protocols in surgically assisted rapid maxillary expansion by finite element analysis
(2024)Background and Objectives: Transverse maxillary deficiency is an important maxillary anomaly that is very common in society and remains current in orthodontics. The maxillary expansion has been used in treatment for a ... -
Structural properties of rat intestinal fatty acid-binding protein with its dynamics: Insights into intrinsic disorder
(2024)Background: The rat intestinal fatty acid-binding protein (I-FABP) is expressed in the small intestine and is involved in the absorption and transport of dietary fatty acids. It is used as a marker for intestinal injury ... -
Intrinsically disordered proteins by homology modeling and replica exchange molecular dynamics simulations: A case study of amyloid-β42
(2024)Homology modeling emerges as a potent tool unveiling the structural enigma of intrinsically disordered proteins (IDPs), with recent advancements such as AlphaFold2 enhancing the precision of these analyses. The process ... -
Liquid-Liquid Phase Separation Associated with Intrinsically Disordered Proteins: Experimental and Computational Tools
(2024)The phenomenon of Liquid-Liquid Phase Separation (LLPS) serves as a vital mechanism for the spatial organization of biomolecules, significantly influencing the elementary processes within the cellular milieu. Intrinsically ... -
Structures prediction and replica exchange molecular dynamics simulations of α-synuclein: A case study for intrinsically disordered proteins
(2024)In recent years, a variety of three-dimensional structure prediction tools, including AlphaFold2, AlphaFold3, ITASSER, C-I-TASSER, Phyre2, ESMFold, and RoseTTAFold, have been employed in the investigation of intrinsically ... -
Solar-hydrogen coupling hybrid systems for green energy
(Wiley, 2023)Green hydrogen production coupled with solar energy became a universal concept to provide more efficient energy caring for the environment within the 2030 sustainable development goals target. The green energy concept ... -
Investigation of a novel & integrated simulation model for hydrogen production from lignocellulosic biomass
(2018)Process simulation and modeling works are very important to determine novel design and operation conditions. In this study; hydrogen production from synthesis gas obtained by gasification of lignocellulosic biomass is ... -
Photocatalytic water oxidation with a Prussian blue modified brown TiO2
(2021)A recently emerging visible light-absorbing semiconductor, brown TiO2 (b-TiO2), was coupled with a CoFe Prussian blue (PB) analogue to prepare an entirely earth-abundant semiconductor/water oxidation catalyst hybrid assembly. ...
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