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Recent Submissions
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The prolonged effect of Kinesio Taping on joint torque and muscle activity
(Taylor & Francis Ltd, 2022)PurposeAlthough Kinesio Taping has been extensively used, evidence about the effect of Kinesio Taping is still insufficient. The aim is to determine the effect of Kinesio Taping on elbow joint torque and muscle activity ... -
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ... -
Classification of breast cancer histopathological images using DenseNet and transfer learning
(Hindawi Publishing Corporation, 2022)Breast cancer is one of the most common invading cancers in women. Analyzing breast cancer is nontrivial and may lead to disagreements among experts. Although deep learning methods achieved an excellent performance in ... -
Production of rare earth element oxide powders by solution combustion: a new approach for recycling of NdFeB magnets
(Royal Society of Chemistry, 2022)NdFeB magnets are employed in various technological applications due to their outstanding magnetic properties, such as high maximum energy product, high remanence and high coercivity. Production of NdFeB has gathered more ... -
Optimization and predictive modeling of reinforced concrete circular columns
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Metaheuristic optimization techniques are widely applied in the optimal design of structural members. This paper presents the application of the harmony search algorithm to the optimal dimensioning of reinforced concrete ... -
Sensitivity of muscle force response of a two-state cross-bridge model to variations in model parameters
(Sage Publications, 2022)Muscle models based on the cross-bridge theory (Huxley-type models) are frequently used to calculate muscle forces for different contractile conditions. Dynamic and nonlinear characteristics of muscle forces produced during ... -
Optimal dimensioning of retaining walls using explainable ensemble learning algorithms
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)This paper develops predictive models for optimal dimensions that minimize the construction cost associated with reinforced concrete retaining walls. Random Forest, Extreme Gradient Boosting (XGBoost), Categorical Gradient ... -
Molecularly imprinted polymer based sensors for SARS-CoV-2: where are we now?
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome ... -
Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia
(American Chemical Society, 2022)The S59L genetic mutation of the mitochondrial coiled-coil-helix-coiled-coil-helixdomain-containing protein 10 (CHCHD10) is involved in the pathogenesis of amyotrophic lateralsclerosis (ALS) and frontotemporal dementia ... -
Interpretable machine learning algorithms to predict the axial capacity of frp-reinforced concrete columns
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Fiber-reinforced polymer (FRP) rebars are increasingly being used as an alternative to steel rebars in reinforced concrete (RC) members due to their excellent corrosion resistance capability and enhanced mechanical properties. ... -
NFI transcriptionally represses CDON and is required for SH-SY5Y cell survival
(Elsevier, 2022)Nuclear Factor One (NFI) family of transcription factors regulate proliferation and multiple aspects of differentiation, playing analogous roles in embryonic development and various types of cancer. While all NFI family ... -
Ion-imprinted polymer-on-a-sensor for copper detection
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)The accumulation of metal ions in the body is caused by human activities and industrial uses. Among these metal ions, copper is the third most abundant ion found in the human body and is indispensable for health because ... -
The effect of preceramic soldering on fracture resistance of 4-unit zirconia fixed dental prostheses
(Wiley, 2022)Purpose Preceramic soldering of zirconia may deliver better fitting restorations. However, there is not sufficient evidence regarding the influence of preceramic soldering of zirconia restorations on mechanical strength. ... -
Secondary structure dependence of amyloid-beta(1-40) on simulation techniques and force field parameters
(Wiley, 2021)Our recent studies revealed that none of the selected widely used force field parameters and molecular dynamics simulation techniques yield structural properties for the intrinsically disordered alpha-synuclein that are ... -
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation
(Wiley, 2021)ProA is a secreted zinc metalloprotease of Legionella pneumophila causing lung damage in animal models of Legionnaires' disease. Here we demonstrate that ProA promotes infection of human lung tissue explants (HLTEs) and ... -
Microbial peptidyl-prolyl cis/trans isomerases (ppIases): virulence factors and potential alternative drug targets
(Amer Soc Microbiology, 2014)Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases (PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at peptidyl bonds preceding proline ... -
Polyketide synthase (PKS) reduces fusion of Legionella pneumophila-containing vacuoles with lysosomes and contributes to bacterial competitiveness during infection
(Elsevier Gmbh, Urban & Fischer Verlag, 2014)L. pneumophila-containing vacuoles (LCVs) exclude endocytic and lysosomal markers in human macrophages and protozoa. We screened a L. pneumophila mini-Tn10 transposon library for mutants, which fail to inhibit the fusion ... -
Novel cycloheximide derivatives targeting the moonlighting protein Mip exhibit specific antimicrobial activity against Legionella pneumophila
(Frontiers Media Sa, 2015)Macrophage infectivity potentiator (Mip) and Mip-like proteins are virulence factors in a wide range of pathogens including Legionella pneumophila. These proteins belong to the FK506 binding protein (FKBP) family of ... -
Peptidylprolyl cis-trans isomerases of Legionella pneumophila: virulence, moonlighting and novel therapeutic targets
(Portland Press Ltd, 2014)Legionella pneumophila, typically a parasite of free-living protozoa, can also replicate in human alveolar macrophages and lung epithelial cells causing Legionnaires' disease in humans, a severe atypical pneumonia. The ... -
The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions
(Royal Soc, 2015)Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes. Here, we describe ...
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