Electromagnetic investigation of neuron growth by using pulsed electromagnetic field stimulation

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dc.authorid0000-0002-3399-9346
dc.contributor.authorKara, S.
dc.contributor.authorUzunoğlu, C. P.
dc.contributor.authorİşçi, E. T.
dc.contributor.authorAtalar, F.
dc.contributor.authorUğur, Mukden
dc.date.accessioned2024-04-04T13:05:32Z
dc.date.available2024-04-04T13:05:32Z
dc.date.issued2023
dc.departmentTAÜ, Fen Bilimleri Enstitüsü, Robotlar ve Akıllı Sistemler Ana Bilim Dalı Koleksiyonuen_US
dc.description.abstractElectromagnetic field (EMF) applications for humans have been widely used for medical therapy for a long time. Various nerve diseases such as complex regional pain syndrome, cerebral palsy and spinal cord injuries may occur as a result of damage on the nerve cells. In addition, EMF applications are taken into consideration in terms of tissue regeneration. The use of electricity for nerve regeneration is applied internally or externally. The use of direct current (DC) electric fields to stimulate axon elongation and nerve regeneration in nerve cells has been applied in various studies. In our study, electromagnetic field was used for the controlled and directional growth of Dorsal Root Ganglia (DRG) nerve cells. An amplifier circuit, which can produce amplified signals to generate proposed pulsed electromagnetic fields (PEMF) is designed. The electromagnetic field is produced on FR-4 copper plate, which highlights electrical field unlike previous studies, since there is no circular coil structure preferred. The elongation of nerve cells is planned to be in one direction, hence the signal to be applied is produced as a novel asymmetrical waveform (sawtooth) in addition to triangular and square waveforms which were previously preferred in recent studies. By the aid of proposed novel construction and produced signal waveform, PEMF system can be applied for nerve diseases effectively. The morphological nerve cell elongation results and PEMF results have been investigated and the effectiveness of the proposed system is verified.
dc.identifier.citationUğur, M., Kara, S. Uzunoğlu, C. P., İşçi, E. T., Atalar, F. (2023). Electromagnetic investigation of neuron growth by using pulsed electromagnetic field stimulation. Biomedical Signal Processing and Control içerisinde 84. Elsevier BV.
dc.identifier.doi10.1016/j.bspc.2023.104739
dc.identifier.scopus2-s2.0-85149056997
dc.identifier.urihttps://hdl.handle.net/20.500.12846/996
dc.identifier.wosWOS:000964811600001
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofBiomedical Signal Processing and Control
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDRGen_US
dc.subjectNeuron growthen_US
dc.subjectPEFen_US
dc.subjectElectromagnetic analysisen_US
dc.titleElectromagnetic investigation of neuron growth by using pulsed electromagnetic field stimulation
dc.typeArticle

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