Yazar "Scheller, Frieder W." için listeleme
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Au-Pt nanoparticles based molecularly imprinted nanosensor for electrochemical detection of the lipopeptide antibiotic drug Daptomycin
In this work, a novel electrochemical molecularly imprinted polymer (MIP) sensor for the detection of the lipopeptide antibiotic Daptomycin (DAP) is presented which integrates gold decorated platinum nanoparticles (Au-Pt ... -
Electrochemical MIP sensor for butyrylcholinesterase
Özçelikay, Göksu; Kurbanoğlu, Sevinç; Zhang, Xiaorong; Söz, Çağla; Wollenberger, Ulla; Özkan, Sibel Ayşıl; Scheller, Frieder W. (Mdpi, 2019)Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically ... -
Electrochemical MIP sensors for environmental analysis
Yarman, Aysu; Kurbanoğlu, Sevinç; Zhang, Xiaorong; Scheller, Frieder W. (Springer, 2023)[Özet yok] -
Electrochemical MIP-sensors for drugs
Yarman, Aysu; Kurbanoğlu, Sevinç; Jetzschmann, Katharina J.; Özkan, Sibel A.; Wollenberger, Ulla; Scheller, Frieder W. (Bentham Science Publ Ltd, 2018)In order to replace bio-macromolecules by stable synthetic materials in separation techniques and bioanalysis biomimetic receptors and catalysts have been developed: Functional monomers are polymerized together with the ... -
Electrochemical readout of molecularly imprinted polymers: potentials and challenges
Yarman, Aysu; Özçelikay, Göksu; Kurbanoğlu, Sevinç; Peng, Lei; Söz, Çağla; Özkan, Sibel Ayşıl; Wollenberger, Ulla; Scheller, Frieder W. (2020)Molecularly imprinted polymers (MIPs) are one of the most frequently studied alternative recognition elements in chromatography and sensorics. They are prepared by polymerizing the target analyte (socalled template) and ... -
Electrosynthesized MIPs for transferrin: Plastibodies or nano-filters?
Zhang, Xiaorong; Yarman, Aysu; Erdossy, Julia; Katz, Sagie; Zebger, Ingo; Jetzschmann, Katharina J.; Scheller, Frieder W. (Elsevier Advanced Technology, 2018)Molecularly imprinted polymer (MP) nanofilrns for transferrin (Trf) have been synthesized on gold surfaces by electro-polymerizing the functional monomer scopoletin in the presence of the protein target or around pre-adsorbed ... -
Enzymes as tools in MIP-Sensors
Yarman, Aysu; Jetzschmann, Katharina J.; Neumann, Bettina; Zhang, Xiaorong; Wollenberger, Ulla; Cordin, Aude; Scheller, Frieder W. (Mdpi, 2017)Molecularly imprinted polymers (MIPs) have the potential to complement antibodies in bioanalysis, are more stable under harsh conditions, and are potentially cheaper to produce. However, the affinity and especially the ... -
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
Zhang, Xiaorong; Waffo, Armel T.; Yarman, Aysu; Kovacs, Norbert; Bognar, Zsofia; Wollenberger, Ulla; El-Sherbiny, Ibrahim M.; Hassan, Rabeay Y. A.; Bier, Frank F.; Gyurcsanyi, Robert E; Zebger, Ingo; Scheller, Frieder W. (Royal Society of Chemistry, 2022)Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ... -
How reliable is the electrochemical readout of MIP sensors?
Yarman, Aysu; Scheller, Frieder W. (Sensors,, 2020)Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by ... -
Insights in electrosynthesis, target binding, and stability of peptide-imprinted polymer nanofilms
Yarman, Aysu; Caserta, Giorgio; Gyurcsányi, Róbert E.; Wollenberger, Ulla; Zhang, Xiaorong; Zebger, Ingo; Supala, Eszter; Scheller, Frieder W. (2021)Molecularly imprinted polymer (MIP) nanofilms have been successfully implemented for the recognition of different target molecules: however, the underlying mechanistic details remained vague. This paper provides new ... -
Label-Free MIP sensors for protein biomarkers
Zhang, Xiaorong; Jetzschmann, Katharina; Yarman, Aysu; Scheller, Frieder W.; Wollenberger, Ulla (Springer, 2017)[Özet yok] -
MIPs and aptamers for recognition of proteins in biomimetic sensing
Menger, Marcus; Yarman, Aysu; Erdossy, Julia; Yıldız, Hüseyin Bekir; Gyurcsanyi, Robert E.; Scheller, Frieder W. (Mdpi, 2016)Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides ... -
Molecular LEGO by domain-imprinting of cytochrome P450 BM3
Jetzschmann, Katharina J.; Yarman, Aysu; Rustam, L.; Kielb, P.; Urlacher, V. B.; Fischer, A.; Scheller, Frieder W. (Elsevier Science Bv, 2018)Hypothesis: Electrosynthesis of the MIP nano-film after binding of the separated domains or holocytochrome BM3 via an engineered anchor should result in domain-specific cavities in the polymer layer. Experiments: Both the ... -
Molekularer abdruck oder selektion bei der erzeugung biomimetischer specifyer
Oktay, Aysel; Menger, Marcus M.; Yarman, Ayşe; Scheller, Frieder W. (Springer, 2023)Zum Ersatz oder auch zur Ergänzung von Antikörpern für niedermolekulare Substanzen wie Antibiotika, Umweltgifte und Pharmaka, aber auch für Proteinbiomarker, Viren und Mikroorganismen in Trennungstechniken, Diagnostik und ... -
“Out of pocket” protein binding—A dilemma of epitope imprinted polymers revealed for human hemoglobin
Zhang, Xiaorong; Caserta, Giorgio; Supala, Eszter; Wollenberger, Ulla; Gyurcsányi, Róbert E.; Zebger, Ingo; Scheller, Frieder W.; Yarman, Aysu (2021)The epitope imprinting approach applies exposed peptides as templates to synthesize Molecularly Imprinted Polymers (MIPs) for the recognition of the parent protein. While generally the template protein binding to such ... -
Peptide epitope-imprinted polymer microarrays for selective protein recognition. Application for SARSCoV-2 RBD protein
Yarman, Aysu; Bognar, Zso´fia; Supala, Eszter; Zhang, Xiaorong; Bier, Frank F.; Scheller, Frieder W.; Gyurcsanyi, Robert E. (2022)We introduce a practically generic approach for the generation of epitope-imprinted polymer-based microarrays for protein recognition on surface plasmon resonance imaging (SPRi) chips. The SPRi platform allows the ... -
Present state of MIP-based sensors for SARS-CoV-2
Yarman, Aysu; Kurbanoğlu, Sevinç; Scheller, Frieder W. (Elsevier, 2022)[Özet yok] -
Simple and robust: The claims of protein sensing by molecularly imprinted polymers
A spectrum of 7562 publications on Molecularly Imprinted Polymers (MIPs) has been presented in literature within the last ten years (Scopus, September 7, 2020). Around 10 % of the papers published on MIPs describe ...
