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Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice
Uluca, Betül; Schmidt, Ulrike; Vokic, Iva; Malik, Barizah; KolbeI, Thomas; Lassnig, Caroline; Holcmann, Martin; Moreno-Viedma, Veronica; Robl, Bernhard; Muhlberge, Carina; Gotthard, Dagmar; Sibilia, Maria; Müller, Mathias; Csisza, Agnes; Rülick, Thomas (2023)FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient ...