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Current challenges and limitations in the studies of intrinsically disordered proteins in neurodegenerative diseases by computer simulations

Akbayrak, İbrahim Yağız; Çağlayan, Şule İrem; Özcan, Zilan; Uversky, Vladimir; Weber, Orkide Coşkuner (Bentham Science Publishers, 2020)

Experiments face challenges in the analysis of intrinsically disordered proteins in solution due to fast conformational changes and enhanced aggregation propensity. Computational studies complement experiments, being widely ...