Tissue regeneration processing and mimicking

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dc.authorid0000-0002-3729-3551
dc.contributor.authorOktay, Aysel
dc.contributor.authorOktay, Büşra
dc.contributor.authorDurası, Elif
dc.contributor.authorÇalık, Hilal
dc.contributor.authorTenim, İlkay
dc.contributor.authorYılmaz, Rabia Öztürk
dc.contributor.authorAydın, Rüveyda
dc.contributor.authorMahouti, Tarlan
dc.contributor.authorYılmazer, Hakan
dc.contributor.authorÇakır, Rabia Koç
dc.date.accessioned2023-10-23T13:10:25Z
dc.date.available2023-10-23T13:10:25Z
dc.date.issued2023
dc.departmentTAÜ, Fen Fakültesi, Moleküler Biyoteknoloji Bölümüen_US
dc.description.abstractTissue regeneration has been one of the comprehensive topics that underlie tissue engineering and has been researched over years. The main aim in tissue engineering is to create a tissue microenvironment produced from natural or synthetic biomaterials, to promote tissue regeneration in the injured site, thus mimicking the natural extracellular matrix (ECM) structure as much as possible, to ensure the migration of specific cells to the site, cell proliferation, and cell differentiation. In this context, it is critical to understand the difference between tissue repair and tissue regeneration, the main stages of tissue repair (hemostasis, inflammation, proliferation and remodeling), and the regeneration and repair mechanisms of the four basic tissues (connective, epithelial, muscle, and nerve tissue). Studies on tissue regeneration mainly focus on scaffolds, decellularized tissues, and their combination with cells capable of self-renewal and differentiation, such as stem cells. Herein, it is also presented in detail how to mimic the tissue microenvironment, the essential characteristics of a scaffold and why decellularized tissues are needed.
dc.identifier.citationOktay, Aysel. Oktay, Büşra. Durası, Elif. Çalık, Hilal. Tenim, İlkay. Yılmaz, Rabia Öztürk. Aydın, Rüveyda. Mahouti, Tarlan. Yılmazer, Hakan. Çakır, Rabia Koç (2023). Tissue regeneration processing and mimicking. Biomaterials and Tissue Engineering. (31-72). Wiesbaden: Springer Cham.
dc.identifier.doi10.1007/978-3-031-35832-6_2
dc.identifier.endpage72en_US
dc.identifier.isbn9783031358326
dc.identifier.startpage31en_US
dc.identifier.urihttps://link.springer.com/chapter/10.1007/978-3-031-35832-6_2
dc.identifier.urihttps://hdl.handle.net/20.500.12846/743
dc.language.isoen
dc.publisherSpringer Cham
dc.relation.ispartofBiomaterials and Tissue Engineering
dc.relation.publicationcategoryKitap Bölümü - Ulusal
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectTissue regenerationen_US
dc.subjectTissue repairen_US
dc.subjectTissue microenvironmenten_US
dc.subjectMimickingen_US
dc.subjectScaffolden_US
dc.subjectDecellularizationen_US
dc.titleTissue regeneration processing and mimicking
dc.typeBook Part

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