Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer’xxs and Parkinson’xxs diseases
Yükleniyor...
Tarih
2019
Dergi Başlığı
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Yayıncı
Academic Press
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
Açıklama
Anahtar Kelimeler
Kaynak
Dancing protein clouds: Intrinsically disordered proteins in health and disease, Part A, Volume 166
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Künye
Uversky, Vladimir N., Coşkuner Weber, O. (2019). Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer’xxs and Parkinson’xxs diseases. Dancing protein clouds: Intrinsically disordered proteins in health and disease, Part A, Volume 166. Academic Press.
