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Öğe Examination of paraffin-embedded testes of domestic cats and dogs by light and scanning electron microscopy(Elsevier BV, 2025-06) Banu Kandil; Beste Demirci; Alev Gürol Bayraktaroğlu; Emre DemirciThis study was designed to determine the appropriate section thickness for SEM analysis of paraffin-embedded testes. This study used paraffin-embedded testes from 6 adult cats and 6 adult dogs. Tissue blocks were cut into 10, 20, and 40 µm thick sections and analyzed by SEM. In addition, seminiferous tubule and lumen diameter and germinative epithelium height were measured in 10 and 20 µm thick paraffin sections. Measurements from 10 and 20 µm thick paraffin sections showed that the height of the germinative epithelium and the diameter of the lumen and tubules were similar between cats and dogs (p > 0.05). In cats and dogs, tubule diameter and germinative epithelium height were higher in the 10 µm thick paraffin sections compared to the 20 µm thick paraffin sections. However, in both species, the lumen diameter was greater in the 20 µm thick paraffin sections than in the 10 µm thick paraffin sections (p < 0.05). Unlike 40 µm thick paraffin sections, 10 and 20 µm thick paraffin sections allowed the structural features of the testes to be examined. Additionally, 10 µm thick paraffin sections were ideal for histometric measurements, while 20 µm thick paraffin sections were suitable for detailed examination of late spermatids. The present study showed that testes may be examined in detail by SEM from 10 and 20 µm thick paraffin sections. In addition, this study may contribute to the design of new studies to reveal the missing three-dimensional structures of paraffin-embedded testicular tissues stored in tissue archives by analyzing them by SEM.Öğe Online Education on Sustainable Nutrition Affects Women's Sustainable Eating Behavior and Anthropometric Measures(Wiley, 2025-03-12) Gülsüm Şahin‐Bodur; Esra Tunçer; Emre Duman; Selen Yilmaz; Alev KeserObjective: To determine the effect of online sustainable nutrition education (SNE) on sustainable eating behaviors and anthropometric measurements in women. Design: In the research, a pretest-posttest quasi-experimental design was used for groups that were subjected to two different trainings. Sample: In the education group, 34 and in the control group, 51 women that between the ages of 19-50 years from six Women's Education and Culture Centers of Ankara Altındağ Municipality. Intervention: After the pretest, the Healthy Nutrition Education (HNE) group received one session of education on "healthy eating" in the second week of the study, while the SNE group received one session of education on "healthy eating" in the second week and "sustainable nutrition" in the third and fourth weeks. Participants were given SNE and its effectiveness was evaluated after 10 weeks. Results: At the end of 10 weeks, body fat percentage decreased significantly from 35.0 ± 6.7 to 33.7 ± 6.8 in the SNE group (p = 0.007). In addition, muscle mass (kg) increased significantly from 43.4[6] to 44.7[5.2] in the SNE group (p = 0.001). When covariance analysis was performed by correcting for body mass index, the group factor had an effect on body fat percentage and muscle mass (p = 0.035 and p = 0.007, respectively). After 10 weeks, the SNE group had a higher Sustainable and Healthy Eating Behaviors Scale mean score (p = 0.013), seasonal foods and avoiding food waste (p = 0.044), animal health (p = 0.003), reducing meat consumption (p = 0.022), healthy and balanced nutrition (p = 0.031), and low fat (p < 0.001) scores compared to HNE group. Conclusions: The dissemination of structured nutrition education for women is important for individuals and, thus, society to acquire and maintain positive eating practices that have an impact on physical health.Öğe The Role of Energy Homeostasis-Associated Gene Expression and Serum Adropin Levels in Patients with Familial Mediterranean Fever(MDPI AG, 2025-03-06) Durkadin Demir Eksi; Gulay Gulbol Duran; Muhammet Murat Celik; Yunus Emre Eksi; Ramazan GunesacarFamilial Mediterranean Fever (FMF) is a genetic autoinflammatory disease primarily affecting populations in the Mediterranean region. The pathogenesis of FMF and the roles of various molecules remain unclear. Adropin, a protein encoded by the Energy Homeostasis-Associated Gene (ENHO), is involved in energy metabolism and inflammation. This study aimed to explore the relationship between ENHO expression, Adropin levels, and FMF, examining their correlations with disease characteristics. This study included 30 patients clinically diagnosed with FMF and 35 healthy controls. The ENHO expression in peripheral blood mononuclear cells was assessed using a qRT-PCR, and the serum Adropin levels were measured via ELISA. The ENHO expression was significantly elevated in the FMF patients compared to the controls (p = 0.0007), while no significant differences were observed in the serum Adropin levels between the groups (p = 0.81). A correlation analysis revealed a negative association between the ENHO expression and age (r = -0.47, p = 0.009), whereas the serum Adropin levels were positively correlated with age, disease onset, and diagnostic delay (p < 0.05). No significant associations were found between the ENHO expression and Adropin levels or FMF clinical features. These findings suggest that increased ENHO expression may play a role in FMF pathophysiology, potentially as a compensatory mechanism. The correlation between Adropin levels and disease onset indicates a potential protective role. Further studies are needed to confirm these findings.Öğe Resilience and meaning-centered coping as mediators in the relationship between life satisfaction and posttraumatic outcomes among earthquake survivors in Turkey.(2025-03-07) Türk, Nuri; Yildirim, Murat; Batmaz, Hasan; Aziz, Izaddin Ahmad; Gómez-Salgado, JuanThis study aimed to examine the mediating roles of resilience and meaning-centered coping in the relationships between life satisfaction and posttraumatic growth and depreciation. The sample consisted of 255 participants (70% females, Mage = 23.35), who directly experienced the earthquakes that occurred in Turkey on February 6, 2023. Using an online survey, participants answered self-reported questions about their perceived life satisfaction, posttraumatic growth, depreciation, resilience, and meaning-centered coping. Findings showed that life satisfaction significantly predicted resilience, meaning-centered coping, and posttraumatic depreciation. Resilience and meaning-centered coping significantly predicted both posttraumatic growth and depreciation. Importantly, resilience and meaning-centered coping significantly mediated the association of life satisfaction with posttraumatic growth and depreciation. In conclusion, the findings of this study have important implications for customizing interventions designed to enhance the resilience and coping mechanisms of individuals dealing with traumas, including those with posttraumatic stress disorder.Öğe Immunohistochemical Distribution of Heat Shock Proteins 27, 60, 70 and 90 in the Placenta of Goats in the Second and Third Trimester of Pregnancy(Wiley, 2025-02-27) Banu KandilDetermining the immunoexpression of HSPs in the placenta may contribute to the understanding of pregnancy physiology and immunotolerance mechanisms. This study aimed to determine the distribution of HSP27, HSP60, HSP70 and HSP90 in the placenta of goats. Tissue samples were taken from the placentomal and interplacentomal regions of the pregnant uterus of 12 goats, comprising 6 s and 6 third trimesters. Following routine histological procedures, immunohistochemical staining was performed on tissue sections. In the interplacentomal region, HSP27, HSP60, HSP70 and HSP90 in luminal and glandular epithelial, stromal and smooth muscle cells did not show differences between the second and third trimesters (p > 0.05). In the placentomal region, HSP27 and HSP60 in syncytial plaques and HSP27, HSP60, HSP70, and HSP90 in maternal stromal cells did not change as the pregnancy progressed (p > 0.05). There was no difference in HSP27, HSP60 and HSP90 in fetal stromal cells between the second and third trimesters (p > 0.05). HSP27 and HSP90 were positive in both trophoblast cells, HSP60 was positive in binucleate trophoblast cells, and HSP70 was positive in mononucleate trophoblast cells. In the third trimester compared with the second trimester, HSP27 was decreased (p < 0.05), while HSP90 in mononucleate and binucleate trophoblast cells did not show a difference (p > 0.05). HSP70 did not change in mononucleate trophoblast cells (p > 0.05), but HSP60 was increased in binucleate trophoblast cells (p < 0.05) as the pregnancy progressed. In conclusion, this study showed that HSPs had similar immunoexpression patterns in the interplacentomal region but different immunoexpression patterns in the placentomal region of the goat placentaÖğe Interpretable Artificial Intelligence for Analysing Changes in Gases in the Uterine Environment of Cows According to Physiological Structures in the Ovary(Wiley, 2025-02-19) Ali Risvanli; Burak Tanyeri; Güngör Yildirim; Yetkin Tatar; Mehmet Gedikpinar; Hakan Kalender; Tarik Safak; Burak Yuksel; Burcu Karagulle; Oznur Yilmaz Koç; Cebrail Barut; Mehmet Akif KilincThe objective of the present study was to examine the relationship between the gases in a cow's uterine environment and its ovarian physiological structures using the sunflower optimisation algorithm (SFOA) deployed in a device called Metrisör, developed by our project team. A total of 500 uteruses obtained from slaughtered cows served as the experimental sample. Gas measurements were taken from 489 uteruses with no clinical metritis or microbiological growth. Additionally, the diameters of the corpus luteum and follicles in the ovaries were measured using callipers. These results were then analysed based on the presence or absence of a corpus luteum (CL) and follicles larger or smaller than 1.5 cm. According to uterine gas fluctuations, the presence and absence of CL could be detected at rates of 80.60% and 79.60%, respectively. Also, based on uterine gas changes, the presence of ovarian follicles larger than 1.5 cm was determined 82% of the time, and the presence of follicles smaller than 1.5 cm was determined 80% of the time. In conclusion, it was found that different stages of a cow's sexual cycle might involve changes in uterine gases. Thus, the data from this study may enable the development of a new estrus detection method for cows.Öğe Machine Learning and Shock Indices-Derived Score for Predicting Contrast-Induced Nephropathy in ACS Patients(Ovid Technologies (Wolters Kluwer Health), 2025-02-13) Yunus Emre Yavuz; Sefa Tatar; Hakan Akıllı; Muzaffer Aslan; Abdullah İçliBackground Contrast-induced nephropathy (CIN) is a serious complication following acute coronary syndrome (ACS), leading to increased morbidity and mortality. Machine learning (ML), combined with parameters such as shock indices, can potentially improve CIN risk prediction by analyzing complex variable interactions and creating accessible, clinically applicable models. Methods This retrospective case-control study included 719 ACS patients who underwent percutaneous coronary intervention (PCI). Patients were divided into two groups (CIN and non-CIN), and clinical, procedural, and hemodynamic parameters, including shock indices, were analyzed using machine learning algorithms. A new predictive model, CIN-Predict 5, was developed using the Gradient Boosting Machine (GBM) algorithm, incorporating clinically relevant and statistically significant variables. Correlations between model predictions and secondary outcomes, including in-hospital mortality and hospitalization duration, were evaluated. Results Among the variables used in the GBM algorithm, the Modified Shock Index emerged as the most significant predictor, with an importance score of 0.25. The CIN-Predict 5 model achieved an AUC of 0.87, outperforming the Mehran Risk Score (AUC = 0.75) for predicting CIN. The secondary outcomes showed that CIN-Predict 5 correlated significantly with in hospital mortality (r = 0.16, p < 0.001) and hospitalization duration (r = 0.20, p < 0.001). Conclusions The GBM-based model we developed, utilizing shock indices and derived through ML, provides a practical tool for early identification of high-risk CIN patients post-ACS, enabling timely preventive strategies and improving clinical decision-making. © 2025 Wolters Kluwer Health, Inc. All rights reserved.Öğe Comprehensive experimental and computational analysis of endemic Allium tuncelianum: Phytochemical profiling, antimicrobial activity, and In silico studies for potential therapeutic applications(Elsevier BV, 2025-05) Oğuzhan Özdemir; Nurten Yılmaz; Ahmad Badreddin Musatat; Tuna Demirci; Servet Çete; Emrah Yerlikaya; Mustafa Oğuzhan KayaAllium tuncelianum (TG), an endemic garlic species from Tunceli, Turkey, was investigated using a multidisciplinary approach combining experimental and computational methods. Density Functional Theory (DFT) calculations with B3LYP/def2-SVP/def2-TZVP basis sets were employed to analyze electronic properties, reactivity, and stability under gas and ethanol conditions. Headspace/GC-MS identified 10 major components, with diallyl disulfide (48.03 %) and 1-propene (20.72 %) as predominant. Antimicrobial assays revealed potent activity against MRSA, Salmonella paratyphi A, and E. coli, with MIC values as low as 0.063 mg/mL. Antioxidant capacity, evaluated via DPPH, metal chelating, and FRAP assays, showed promising results, with the water extract exhibiting the highest activity (1.74 mg BHT equivalent/mL). DFT and molecular docking studies highlighted key compounds as potential inhibitors of E. coli Gyrase B, with binding energies of -5.68 and -6.07 kcal/mol. ADME predictions indicated favorable drug-like properties, though some compounds showed potential CYP450 interactions and toxicity. This study provides a comprehensive understanding of TG's biochemical profile and therapeutic potential, offering insights for future research and optimization.Öğe Dynamical analysis of fractional hepatitis B model with Gaussian uncertainties using extended residual power series algorithm(Springer Science and Business Media LLC, 2025-03-07) Qursam Fatima; Mubashir Qayyum; Murad Khan Hassani; Ali AkgülHepatitis B virus (HBV) is a significant global health concern, causing acute and chronic liver diseases, including cirrhosis and hepatocellular carcinoma. This manuscript extends existing mathematical models for HBV by introducing a treatment compartment to improve understanding, diagnosis, and treatment strategies. A stability analysis is conducted for disease-free equilibrium and to address the inherent uncertainties in parameter values, Gaussian fuzzy numbers are incorporated, resulting in a more realistic predictive framework. For solution purposes, the extended residual power series algorithm, which combines the Taylor series with a residual function and an integral transform, is applied. The accuracy of the obtained solutions is assessed by calculating the associated errors. The robustness of the model is further evaluated using r-cut values for lower and upper bounds.A graphical analysis is also performed to examine the influence of different parameters on the solution profiles, enhancing the understanding of disease dynamics. The analysis reveals that the proposed methodology effectively explains the dynamics of epidemic systems and provides new perspectives with potential applications in biology, engineering, and medicine.Öğe Sexual Dimorphism of Foetal Sheep Skulls During the Second and Third Periods of Pregnancy.(2025-03) Güzel, Barış Can; Işbilir, FatmaThe skull is a very important structure, and it is the centre of many vital functions. There have been many studies on the skulls of mammals, but not many studies on the prenatal period. The aim of this study is to examine developmental sheep foetal skulls from the last two trimesters of pregnancy. A total of 40 sheep foetuses, 20 in the 2nd trimester (10 females and 10 males) and 20 in the 3rd trimester (10 females and 10 males), were examined. On the basis of CT scans of foetal skulls, morphometric measurements were performed by creating a three-dimensional (3D) model. Total skull length was statistically significant between males and females in the third trimester (p < 0.01). In the second trimester, the tooth length parameter was statistically significant between males and females (p < 0.01). In the second trimester, M3 was found to be statistically significant in the sheep foetus mandible (p < 0.01). It was determined that there was developmental sexual dimorphism between males and females.Öğe The performance evolution of Xue and Yamada-Ota models for local thermal non equilibrium effects on 3D radiative casson trihybrid nanofluid(Springer Science and Business Media LLC, 2025-03-01) Ahmed M. Galal; Ali Akgül; Sahar Ahmed Idris; Shoira Formanova; Talib K. Ibrahim; Murad Khan Hassani; Abdullah A. Faqihi; Munawar Abbas; Ibrahim MahariqThe proposed study investigates the characteristics of Stefan blowing and activation energy on MHD Casson Diamond-[Formula: see text][Formula: see text]based trihybrid nanofluid over a sheet with LTNECs (local thermal non-equilibrium conditions) and permeable medium. The significance of Marangoni convection as well as heat generation are considered. In order to examine the properties of heat transmission in the absence of local thermal equilibrium conditions, this paper makes use of a simple mathematical model. Local thermal non-equilibrium situations typically result in two discrete and crucial temperature gradients in both the liquid and solid phases. In systems where material qualities and heat transfer efficiency are crucial, the utilization of Xue model and Yamada-Ota model and to assess the thermal conductivity of the nanofluid adds a comparison dimension and enables optimized design. The controlling partial differential equations are reduced to non-linear ordinary differential equations using an appropriate similarity transformation. The Bvp4c technique is used to resolve the resulting equations numerically. Applications in modern thermal management systems, especially those requiring precise heat transfer control (e.g., electronic cooling, medicinal devices, energy systems), will benefit greatly from this work. The model is especially applicable to processes where chemical reactions and internal heat sources are important, like in catalytic reactors and combustion systems, because it takes into account activation energy and heat generating effects. The findings indicate that when the value of the interphase heat transmission factor increases, the solid phase's temperature profile and liquid phase heat transfer rate drop.Öğe From family social support to problematic internet use: a serial mediation model of hostility and depression(Springer Science and Business Media LLC, 2025-02-28) Caner Doğrusever; Mehmet BilginInternet usage has become an inevitable part of daily life. Adolescents who are developmentally vulnerable due to family dynamics or who suffer psychological distress are at greater risk of problematic Internet use. This study aims to reveal the intricate psychological pathways linking family social support to problematic Internet use among adolescents and the mediating roles of hostility and depression. The study uses serial mediation analyses and Hayes PROCESS macro to examine a large sample of 2,047 adolescents (1,182 females and 865 males). Results revealed a significant negative association between family social support and problematic Internet use. Both hostility and depression were found to be critical mediators, functioning independently and sequentially in the relationship between family social support and problematic Internet use. The findings highlight the protective role of family social support against problematic Internet use among adolescents by reducing hostility and depressive symptoms. This investigation contributes to the extant literature by elucidating the psychological mechanisms underlying problematic Internet use. It suggests that interventions targeting family support systems, feelings of hostility, and depression may effectively mitigate problematic Internet use among adolescent populations.Öğe Discharge performance of side gates with different shapes(IWA Publishing, 2025-02-10) Veysi Kartal; M. Emin Emiroglu; M. Fatih YukselFlow measurement and water level control in open channels are vital to water management. Lateral intake structures are commonly used for different purposes in civil and environmental engineering applications. Flow characteristics of rectangular, triangular, and semi-circular shapes were experimentally investigated using 357 runs under subcritical flow conditions. Correlation analysis was conducted to determine the effect of various parameters on the discharge coefficient. Upstream Froude number (F1), the ratio of the gate opening to the upstream flow depth, and the gate length to flow depth ratio are influential for all side gates. However, the ratio of the gate opening to the gate length is also influential for triangular side gates. Discharge coefficient of the semi-circular side gate is relatively higher than that of the other tested gates within the range of 0.05Öğe Uncertainty and Well-Being in Turkish Adults: Exploring the Role of Religiosity and Psychological Symptoms(Springer Science and Business Media LLC, 2025-02-27) Nuri Türk; Gökmen Arslan; Alican Kaya; Oğuzhan YildirimReligiosity offers individuals a sense of purpose and connection, which can lead to greater life satisfaction and improved psychological well-being and happiness. On the other hand, psychological challenges such as depression, anxiety, stress, and difficulty dealing with uncertainty can negatively affect life satisfaction. This study examined these dynamics using a hypothetical model, incorporating mediation and moderation analyses to explore the connections between intolerance of uncertainty, life satisfaction, religiosity, and psychological symptoms in a group of 565 participants (286 of whom were female). The findings revealed notable positive and negative relationships among these variables. Specifically, the study found that (i) religiosity and psychological symptoms both play a mediating role in the link between intolerance of uncertainty and life satisfaction, and (ii) religiosity serves as a moderator in this relationship. The moderation analysis showed that when religiosity levels are low, the negative effect of intolerance of uncertainty on life satisfaction is significantly stronger. In contrast, high levels of religiosity significantly weaken this negative relationship, indicating that religiosity acts as a buffer against the adverse impact of uncertainty on life satisfaction. These results underscore the potential value of religiosity in helping individuals cope with the harmful effects of uncertainty on their sense of life satisfaction. Additionally, lower levels of psychological symptoms and reduced intolerance of uncertainty were associated with higher life satisfaction, suggesting that religiosity may play a protective role in promoting overall well-being.Öğe Wild Emmer (Triticum turgidum ssp. dicoccoides) Diversity in Southern Turkey: Evaluation of SSR and Morphological Variations(MDPI AG, 2025-01-29) Esra Çakır; Ahmad Alsaleh; Harun Bektas; Hakan ÖzkanWild emmer wheat (Triticum turgidum ssp. dicoccoides) is the ancestral species of cultivated tetraploid wheat with BBAA genomes. Because of its full interfertility with domesticated emmer wheat, this wild species can serve as one of the most important genetic resources to improve durum and bread wheat. To clarify the magnitude of genetic diversity between and within populations of Turkish wild emmer wheat, 169 genotypes of ssp. dicoccoides selected from the 38 populations collected from the three sub-regions (East-1, West-1, and West-2) of the Southeast Anatolia Region of Turkey were molecularly and morphologically characterized. The populations showed significant variation in plant height, heading date, flag leaf area, spike length and number, spikelet, peduncle, lemma, palea, glume and anther lengths, glume hull thickness, anther width, and days to maturity. According to the results of nuclear-SSR analysis, the populations collected from the sub-regions East-1 and West-2 were the most genetically distant (0.539), while the populations collected from the sub-regions West-1 and West-2 were the most genetically similar (0.788) populations. According to the results of AMOVA, there was 84% similarity within the populations studied, while the variation between the populations of the three sub-regions was 16%. In the dendrogram obtained by using nuclear-SSR data, the populations formed two main groups. The populations from the sub-region East-1 were in the first group, and the populations from the sub-regions West-1 and West-2 were in the second group. From the dendrogram, it appears that the populations from the sub-region East-1 were genetically distant from the populations from the sub-regions West-1 and West-2. The results highlight the potential diversity in Southeast Anatolia for wild emmer discovery and utilization.Öğe 3D Geometric Morphometric Analysis of Calcaneal Morphology in Domestic Caprinae: Sheep (Ovis aries) and Goat (Capra hircus)(MDPI AG, 2025-02-14) Barış Can Güzel; Tomasz Szara; Burak Ünal; Sokol Duro; Fatma İşbilir; Funda Yiğit; Mihaela-Claudia Spataru; Karolina Goździewska-Harłajczuk; Ozan GündemirThe calcaneus plays a critical role in balance, locomotion, and muscle attachment, making it a key structure for biomechanical adaptations. This study examined interspecies differences between sheep and goats, as well as intraspecies variations among different sheep breeds, in calcaneus morphology. A total of 128 right calcanei were analyzed using 3D geometric morphometric methods to allow detailed assessments of calcaneus shape and size. Among sheep, the Hamdani sheep displayed the largest calcaneus among the breeds, distinguishing them significantly from the others. In contrast, goats had a bilaterally narrower calcaneal body, while sheep featured a more pronounced distal portion that articulates with the talus and a deeper articular surface. Additionally, the sustentaculum tali were more developed in sheep. The bilaterally compressed calcaneal body in goats likely reflects their agility and ability to navigate steep, rocky terrains. In contrast, sheep's broader and more robust calcaneus may support their grazing lifestyle on flatter terrains, emphasizing their stability and weight-bearing capacity. These findings highlight the functional significance of calcaneal morphology in the locomotor strategies and physical capabilities of goats and sheep, providing valuable insights for comparative anatomy and veterinary science.Öğe Abundant soliton solutions in saturated ferromagnetic materials modeled via the fractional Kraenkel–Manna–Merle system(Springer Science and Business Media LLC, 2025-02-25) Loubna Ouahid; Maryam Alshahrani; A. Mohamed Abdel-Baset; M. A. Abdou; Ali Akgül; Murad Khan HassaniThe Modified Generalized Riccati Equation Mapping Technique is employed to discover novel solutions for the Fractional Kraenkel-Manna-Merle system. In this system, a nonlinear of ultra_short wave pulse propagates across saturated ferromagnetic-materials by very low conductance. The beta-derivative is used to analyze the fractional performance of the proposed system. Combo-multi soliton shape, anti-bell-shaped solitons, kink bright-dark shape are the results of the applications. The results obtained are original and unfamiliar to the reader, as they had not been published previously. For a few chosen solutions, two dimensional, and three dimensional are shown to offer important insights into the behavior and properties of the solutions. These detailed exact solutions and wave phenomena contribute to a deeper understanding of this equation. This work opens up new possibilities for exploring wave phenomena in more complexly structured nonlinear.Öğe Skull morphology in native and non-native cattle breeds in Türkiye.(2025-02-23) Gündemir, Ozan; Manuta, Nicoleta; Güzel, Barış Can; Bakıcı, Caner; Duro, Sokol; Ünal, Burak; Çakar, Buket; Szara, TomaszThis study aims to investigate morphological differences in the skulls of cattle breeds with different functional roles and geographical origins and to examine skull shape variations among breeds using geometric morphometrics methods. To this end, 95 skulls from Native (Eastern Anatolian Red and Southern Anatolian Red) and Non-native (Holstein and Simmental) breeds raised in Türkiye were analyzed. The results show a significant size difference between Native Breeds and Non-native Breeds, with the Non-native Breeds having larger skulls. The results also indicate considerable shape differences between Native and Non-native Breeds. No significant shape differences were observed between the two Native Breeds, which have shared the same geography for many years. Although no statistically substantial size difference was found between Simmental and Holstein, the nuchal region showed distinct shape differences. The nuchal part of the Simmental skull was more pronounced than other specimens. In native breeds, there was a more balanced proportion between the facial and neurocranial regions compared to the other two breeds. In Holstein skulls, the facial region was more pronounced in comparison to the neurocranial region, while in Simmental skulls, the neurocranial region was more prominent. This study provides valuable insights into the morphological characteristics of different cattle breeds, contributing to veterinary anatomy, biology, and paleontology.Öğe A new plentiful solutions for nanosolitons of ionic (NSIW) waves spread the length of microtubules in (MLC) living cells(Springer Science and Business Media LLC, 2025-02-20) Loubna Ouahid; M. A. Abdou; Jameelah S. Al Shahrani; A. Mohamed Abdel-Baset; Ali Akgül; Murad Khan HassaniThis article describes the developed Paul-Painlike method (PPM) to provide striking ODE of the nanosoliton of the ionic waves (NSIW) that spread the length of microtubules in live cells. Furthermore, Auxiliary Equation Approach (AEA) and Sardar Sub Equation Approach (SSEA) have been utilized similarly and concurrently to determine solutions for this particular model. In providing a physical explanation, various solitary wave structures are visually represented. These solutions include the anti-kink, kink shape, singular kink wave shape, and periodic bright, bright-dark and dark-singular soliton solution. Additionally, graphical illustrations (both 2-D and 3-D) demonstrate how the various parameters utilized affect the validity of analytical results. Furthermore, the uniqueness of the solutions we derived is highlighted by comparing the differences with earlier solutions of the model. The solutions produced may be beneficial in a number of significant investigations in medicine, as well as biology. The results demonstrate the effectiveness of the proposed techniques for determining many optical solitons of nonlinear evolution equations.Öğe Investigation of the effects of propofol and sevoflurane anesthesia on oxidant-antioxidant status and biochemical parameters in Turkish hair goats(American Veterinary Medical Association (AVMA), 2025-02-17) Ali Gülaydın; Kıvanç İrak; Nihat Şındak; Mustafa Barış Akgül; Özgür Yaşar Çelik; Onur Yıldırım; Maruf Yılmaz; Erman GülendağObjective: To investigate the effects of propofol and sevoflurane anesthesia on the oxidant-antioxidant status and biochemical parameters in Turkish hair goats. Methods: The study was conducted from February 15 through March 15, 2024. Seven clinically healthy female Turkish hair goats aged 1 to 2 years with an average live weight of 29.95 (26.1 to 33.8) kg were included. A bolus of propofol (6 mg/kg) was injected IV. The goats were placed in the sternoabdominal position and administered 1% to 3% sevoflurane with 100% oxygen for 2 hours with the help of a vaporizer. Blood samples were collected before and after the administration of propofol and at the 15th, 30th, 60th, and 120th minutes after the start of sevoflurane administration in nonanticoagulated tubes. The oxidant-antioxidant status (serum total antioxidant status, total oxidant status, paraoxonase activity, and arylesterase activity) and biochemical parameters (levels of glucose, AST, GGT, ALT, ALP, LDH, creatine kinase, amylase, lipase, creatinine, urea, uric acid, high-density lipoprotein, low-density lipoprotein, total protein, albumin, total bilirubin, direct bilirubin, magnesium, chlorine, calcium, iron, sodium, phosphorus, and potassium) were evaluated. The heart rate, respiratory rate, and body temperature of the goats were measured using a bedside monitor. Results: Arylesterase activity increased with sevoflurane administration. Changes were observed in heart rate and body temperature as well as in the levels of glucose, creatine kinase, urea, total bilirubin, and potassium at different time intervals of propofol-sevoflurane administration. Conclusions: Propofol-sevoflurane anesthesia has no adverse effects on oxidant-antioxidant status in Turkish hair goats. Clinical relevance: The evaluation of heart rate and body temperature, as well as glucose, creatine kinase, urea, total bilirubin, and potassium levels, must be considered in propofol-sevoflurane anesthesia protocol.
