The effect of papaverine on tendon healing and adhesion in rats following Achilles tendon repair

Abstract

The Achilles tendon, recognized as the strongest tendon in the human body, plays a pivotal role in transferring the forces generated by the gastrocnemius and soleus muscles to the calcaneus. This complex mechanism is essential for fundamental activities such as walking, jumping, and running.[1,2] Notably, the incidence of acute tendon injuries tends to rise within the age range of 30 to 40 years, predominantly affecting male individuals. These injuries are frequently linked to recreational sports, such as ball games and racket sports, that involve rapid acceleration and jumping.