Tür "article" Moleküler Biyoteknoloji için listeleme
Toplam kayıt 60, listelenen: 1-20
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3In-silico prediction of synergistic anti-cancer drug combinations using multi-omics data
(Nature Publishing Group, 2019)Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two ... -
Acute changes in electrophysiological brain dynamics in elite karate players
(Springer, 2020)Regular physical exercise has enhanced effects on the human anatomy and functionality. Recently, an effect of a single set of exercise is shown to have positive effects on mood and on cognitive functioning. The aim of this ... -
Alanine scanning effects on the biochemical and viophysical properties of intrinsically disordered proteins: a case study of the histidine to alanine mutations in amyloid-beta(42)
(Amer Chemical Soc, 2019)Alanine scanning is a tool in molecular biology that is commonly used to evaluate the contribution of a specific amino acid residue to the stability and function of a protein. Additionally, this tool is also used to ... -
Analysis of correlation between white matter changes and functional responses in thalamic stroke: a DTI & EEG study
(Springer, 2015)Diffusion tensor imaging (DTI) allows in vivo structural brain mapping and detection of microstructural disruption of white matter (WM). One of the commonly used parameters for grading the anisotropic diffusivity in WM is ... -
Application of self-organizing artificial neural networks on simulated diffusion tensor images
(Hindawi Publishing Corporation, 2013)Diffusion tensor magnetic resonance imaging (DTMRI) as a noninvasive modality providing in vivo anatomical information allows determination of fiber connections which leads to brain mapping. The success of DTMRI is very ... -
Au-Pt nanoparticles based molecularly imprinted nanosensor for electrochemical detection of the lipopeptide antibiotic drug Daptomycin
(2020)In this work, a novel electrochemical molecularly imprinted polymer (MIP) sensor for the detection of the lipopeptide antibiotic Daptomycin (DAP) is presented which integrates gold decorated platinum nanoparticles (Au-Pt ... -
BMP-2 and BMP-9 binding specificities with ALK-3 in aqueous solution with dynamics
(Elsevier Science Inc, 2017)Signal ligands of the transforming growth factor-beta (TGF-beta) superfamily include the bone morphogenetic proteins (BMPs). BMPs bind to type I and type II serine-threonine kinase receptors and trigger the transphosphorylation ... -
Challenges and limitations in the studies of glycoproteins: A computational chemist's perspective
(WILEY, 2021)Experimenters face challenges and limitations while analyzing glycoproteins due to their high flexibility, stereochemistry, anisotropic effects, and hydration phenomena. Computational studies complement experiments and ... -
Classification of brain electrophysiological changes in response to colour stimuli
(Springer, 2021)In this study, the classification of ongoing brain activity occurring as a response to colour stimuli was managed and reported. Until now, the classification of the seen colour from brain electrical signals has not been ... -
Coherent organization in gene regulation a study on six networks
(2016)Structural and dynamical fingerprints of evolutionary optimization in biological networks are still unclear. Here we analyze the dynamics of genetic regulatory networks responsible for the regulation of cell cycle and cell ... -
Corrosion response and biocompatibility of graphene oxide (GO)–serotonin (Ser) coatings on Ti6Al7Nb and Ti29Nb13Ta4.6Zr (TNTZ) alloys fabricated by electrophoretic deposition (EPD
(Materials Today Communications, 2023)In this study, Ti6Al7Nb and Ti29Nb13Ta4.6Zr (TNTZ) alloys coated with graphene oxide (GO) and serotonin (Ser) by electrophoretic deposition (EPD) technique were evaluated for possible usage as an orthopedic implant in terms ... -
Covalent dimerization of interleukin-like epithelial-to-mesenchymal transition (EMT) inducer (ILEI) facilitates EMT, invasion, and late aspects of metastasis
(2017)The interleukin-like epithelial-to-mesenchymal transition (EMT) inducer(ILEI)/FAM3C is a member of the highly homologous FAM3 family andis essential for EMT and metastasis formation. It is upregulated in severalcancers, ... -
Current stage and future perspectives for homology modeling, molecular dynamics simulations, machine learning with molecular dynamics, and quantum computing for intrinsically disordered proteins and proteins with intrinsically disordered regions
(2024)The structural ensembles of intrinsically disordered proteins (IDPs) and proteins with intrinsically disordered regions (IDRs) cannot be easily characterized using conventional experimental techniques. Computational ... -
Çörek Otu’nun (Nigella sativa) biyolojik ve farmakolojik özellikleri
(Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, 2023)Ranunculaceae familyasının bir üyesi olan Nigella sativa, Güney Avrupa ve Batı Asya’da doğal olarak yetişen ve dünyanın birçok bölgesinde kültive edilen tek yıllık bir bitkidir. Dünya mutfaklarında baharat olarak ... -
Determination of neural fiber connections based on data structure algorithm
(Hindawi Publishing Corporation, 2010)The brain activity during perception or cognition is mostly examined by functional magnetic resonance imaging (fMRI). However, the cause of the detected activity relies on the anatomy. Diffusion tensor magnetic resonance ... -
Development of a larval zebrafish infection model for clostridioides difficile
(Journal Of Visualized Experiments, 2020)Clostridioides difficile infection (CDI) is considered to be one of the most common healthcare-associated gastrointestinal infections in the United States. The innate immune response against C. difficile has been described, ... -
Development of a molecularly imprinted polymer-based electrochemical sensor for tyrosinase
(Scientific & Technical Research Council Turkey-TUBITAK, 2018)For the first time a molecularly imprinted polymer (MIP)-based sensor for tyrosinase is described. This sensor is based on the electropolymerization of scopoletin or o-phenylenediamine in the presence of tyrosinase from ... -
Editorial
(Elsevier BV, 2023)This special issue on biosensors and protein electrochemistry is dedicated to Professor Frieder W. Scheller on occasion of his 80th birthday in August 2022. Frieder Scheller’s contributions to the field of bioelectroc ... -
Effects of the Jokela type of spinal muscular atrophy-relatedG66V mutation on the structural ensemble characteristics ofCHCHD10
(2023)The G66V pathological variant of the coiled-coil-helix-coiled-coil-helix domain-containing protein 10 (CHCHD10), mitochondrial, plays a role in Jokela type spinalmuscular atrophy. The wild-type and G66V mutant-type CHCHD10 ... -
Electrosynthesized MIPs for transferrin: Plastibodies or nano-filters?
(Elsevier Advanced Technology, 2018)Molecularly imprinted polymer (MP) nanofilrns for transferrin (Trf) have been synthesized on gold surfaces by electro-polymerizing the functional monomer scopoletin in the presence of the protein target or around pre-adsorbed ...