WoS Q Kategorisi "Q2" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
Toplam kayıt 13, listelenen: 1-13
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BMP-2 and BMP-9 binding specificities with ALK-3 in aqueous solution with dynamics
(Elsevier Science Inc, 2017)Signal ligands of the transforming growth factor-beta (TGF-beta) superfamily include the bone morphogenetic proteins (BMPs). BMPs bind to type I and type II serine-threonine kinase receptors and trigger the transphosphorylation ... -
Insights into the molecular mechanisms of Alzheimer's and Parkinson's diseases with molecular simulations: understanding the roles of artificial and pathological missense mutations in intrinsically disordered proteins related to pathology
(Mdpi, 2018)Amyloid-beta and alpha-synuclein are intrinsically disordered proteins (IDPs), which are at the center of Alzheimer's and Parkinson's disease pathologies, respectively. These IDPs are extremely flexible and do not adopt ... -
Interpretable machine learning algorithms to predict the axial capacity of frp-reinforced concrete columns
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Fiber-reinforced polymer (FRP) rebars are increasingly being used as an alternative to steel rebars in reinforced concrete (RC) members due to their excellent corrosion resistance capability and enhanced mechanical properties. ... -
Matching algorithm for improving ride-sharing by incorporating route splits and social factors
(Public Library Science, 2020)Increasing traffic congestion and the advancements in technology have fostered the growth of alternative transportation modes such as dynamic ride-sharing. Smartphone technologies have enabled dynamic ride-sharing to thrive, ... -
Optimal dimensioning of retaining walls using explainable ensemble learning algorithms
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)This paper develops predictive models for optimal dimensions that minimize the construction cost associated with reinforced concrete retaining walls. Random Forest, Extreme Gradient Boosting (XGBoost), Categorical Gradient ... -
Optimization and predictive modeling of reinforced concrete circular columns
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Metaheuristic optimization techniques are widely applied in the optimal design of structural members. This paper presents the application of the harmony search algorithm to the optimal dimensioning of reinforced concrete ... -
Peptidylprolyl cis-trans isomerases of Legionella pneumophila: virulence, moonlighting and novel therapeutic targets
(Portland Press Ltd, 2014)Legionella pneumophila, typically a parasite of free-living protozoa, can also replicate in human alveolar macrophages and lung epithelial cells causing Legionnaires' disease in humans, a severe atypical pneumonia. The ... -
Polyketide synthase (PKS) reduces fusion of Legionella pneumophila-containing vacuoles with lysosomes and contributes to bacterial competitiveness during infection
(Elsevier Gmbh, Urban & Fischer Verlag, 2014)L. pneumophila-containing vacuoles (LCVs) exclude endocytic and lysosomal markers in human macrophages and protozoa. We screened a L. pneumophila mini-Tn10 transposon library for mutants, which fail to inhibit the fusion ... -
Production of rare earth element oxide powders by solution combustion: a new approach for recycling of NdFeB magnets
(Royal Society of Chemistry, 2022)NdFeB magnets are employed in various technological applications due to their outstanding magnetic properties, such as high maximum energy product, high remanence and high coercivity. Production of NdFeB has gathered more ... -
Single-shot full strain tensor determination with microbeam X-ray Laue diffraction and a two-imensional energy-dispersive detector
(Int Union Crystallography, 2017)The full strain and stress tensor determination in a triaxially stressed single crystal using X-ray diffraction requires a series of lattice spacing measurements at different crystal orientations. This can be achieved using ... -
Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia
(American Chemical Society, 2022)The S59L genetic mutation of the mitochondrial coiled-coil-helix-coiled-coil-helixdomain-containing protein 10 (CHCHD10) is involved in the pathogenesis of amyotrophic lateralsclerosis (ALS) and frontotemporal dementia ... -
Virtual extensometer analysis of martensite band nucleation, growth, and strain softening in pseudoelastic NiTi subjected to different load cases
(Mdpi, 2018)Pseudoelastic NiTi shape memory alloys exhibit different stress-strain curves and modes of deformation in tension vs. compression. We have recently shown that under a combination of compression and shear, heterogeneous ... -
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation
(Wiley, 2021)ProA is a secreted zinc metalloprotease of Legionella pneumophila causing lung damage in animal models of Legionnaires' disease. Here we demonstrate that ProA promotes infection of human lung tissue explants (HLTEs) and ...