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Toplam kayıt 146, listelenen: 1-10
Pleiotropic clostridioides difficile cyclophilin PpiB controls cysteine-tolerance, toxin production, the central metabolism and multiple stress responses
(Frontiers Media Sa, 2019)
The Gram-positive pathogen Clostridioides difficile is the main bacterial agent of nosocomial antibiotic associated diarrhea. Bacterial peptidyl-prolyl-cis/trans-isomerases (PPlases) are well established modulators of ...
The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions
(Royal Soc, 2015)
Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes. Here, we describe ...
Novel cycloheximide derivatives targeting the moonlighting protein Mip exhibit specific antimicrobial activity against Legionella pneumophila
(Frontiers Media Sa, 2015)
Macrophage infectivity potentiator (Mip) and Mip-like proteins are virulence factors in a wide range of pathogens including Legionella pneumophila. These proteins belong to the FK506 binding protein (FKBP) family of ...
Virtual extensometer analysis of martensite band nucleation, growth, and strain softening in pseudoelastic NiTi subjected to different load cases
(Mdpi, 2018)
Pseudoelastic NiTi shape memory alloys exhibit different stress-strain curves and modes of deformation in tension vs. compression. We have recently shown that under a combination of compression and shear, heterogeneous ...
Tuning the morphology of ZnO nanostructures with the ultrasonic spray pyrolysis process
(Mdpi, 2018)
Nanostructured zinc oxide (ZnO) particles were synthesized by the one step Ultrasonic Spray Pyrolysis (USP) process from nitrate salt solution (Zn(NO3)(2)center dot 6H(2)O). Various influential parameters, from Zn(NO3)(2)center ...
3In-silico prediction of synergistic anti-cancer drug combinations using multi-omics data
(Nature Publishing Group, 2019)
Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two ...
Electrosynthesized MIPs for transferrin: Plastibodies or nano-filters?
(Elsevier Advanced Technology, 2018)
Molecularly imprinted polymer (MP) nanofilrns for transferrin (Trf) have been synthesized on gold surfaces by electro-polymerizing the functional monomer scopoletin in the presence of the protein target or around pre-adsorbed ...
Comprehensive group pile settlement formula based on 3D finite element analyses
(Japanese Geotechnical Soc, 2018)
In the past, formulas for the settlement of group piles considered only a few input parameters and offered only a limited approximation of the actual settlement. Nowadays, however, thanks to the fast-growing performance ...
Comparison of one dimensional dynamic analysis and microtremor measurement results
(Turkish Chamber Civil Engineers, 2019)
The deformation level of the surface soil layer due to strong ground motion has a considerable effect in soil-structure interaction problems. The shear strain values of the near surface soil deposits which are calculated ...
Açık deniz yapıları kova temel sistemi davranışı üzerinde tekrarlı yük frekansının etkisi
(2018)
Açık deniz yapıları kova temel sistemi davranışının tahmini ile ilgili henüz yeterli bilgi birikimine ulaşılmamıştır. Açık deniz koşullarında temel sistemlerinin ağır tekrarlı yüklere maruz kalması nedeniyle zeminde kalıcı ...