Güncel Gönderiler: Moleküler Biyoteknoloji
Toplam kayıt 83, listelenen: 41-60
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NFI transcriptionally represses CDON and is required for SH-SY5Y cell survival
(Elsevier, 2022)Nuclear Factor One (NFI) family of transcription factors regulate proliferation and multiple aspects of differentiation, playing analogous roles in embryonic development and various types of cancer. While all NFI family ... -
Identification of food/nonfood visual stimuli from event-related brain potentials
(Hindawi Publishing Corporation, 2021)Although food consumption is one of the most basic human behaviors, the factors underlying nutritional preferences are not yet clear. The use of classification algorithms can clarify the understanding of these factors. ... -
Challenges and limitations in the studies of glycoproteins: A computational chemist's perspective
(WILEY, 2021)Experimenters face challenges and limitations while analyzing glycoproteins due to their high flexibility, stereochemistry, anisotropic effects, and hydration phenomena. Computational studies complement experiments and ... -
Classification of brain electrophysiological changes in response to colour stimuli
(Springer, 2021)In this study, the classification of ongoing brain activity occurring as a response to colour stimuli was managed and reported. Until now, the classification of the seen colour from brain electrical signals has not been ... -
Fiziksel performans etkisinde mental aktivitenin elektrofizyolojik bulgularının değerlendirilmesi
(Academic Platform, 2019)Bu çalışmada, zihinsel işyükü paradigmasının yorgunluk ile ilintisine yönelik elektrofizyolojik ölçüm sonuçları iki farklı grup üzerinden incelenmiştir. Ayrık grup olarak, sporcular ve sedanterler ele alınmış olup, bu ... -
Generating simulated DT-MRI dataset
(IGI Global, 2008)Diffusion tensor magnetic resonance imaging (DTMRI), also known as diffusion tensor imaging (DTI), needs post processing by adequate image analysis and visualization tools. White matter tractography using DTI is becoming ... -
Determination of neural fiber connections based on data structure algorithm
(Hindawi Publishing Corporation, 2010)The brain activity during perception or cognition is mostly examined by functional magnetic resonance imaging (fMRI). However, the cause of the detected activity relies on the anatomy. Diffusion tensor magnetic resonance ... -
Analysis of correlation between white matter changes and functional responses in thalamic stroke: a DTI & EEG study
(Springer, 2015)Diffusion tensor imaging (DTI) allows in vivo structural brain mapping and detection of microstructural disruption of white matter (WM). One of the commonly used parameters for grading the anisotropic diffusivity in WM is ... -
Acute changes in electrophysiological brain dynamics in elite karate players
(Springer, 2020)Regular physical exercise has enhanced effects on the human anatomy and functionality. Recently, an effect of a single set of exercise is shown to have positive effects on mood and on cognitive functioning. The aim of this ... -
Improvement of design of a surgical interface using an eye tracking device
(Springer Nature, 2014)Background: Surgical interfaces are used for helping surgeons in interpretation and quantification of the patient information, and for the presentation of an integrated workflow where all available data are combined to ... -
Application of self-organizing artificial neural networks on simulated diffusion tensor images
(Hindawi Publishing Corporation, 2013)Diffusion tensor magnetic resonance imaging (DTMRI) as a noninvasive modality providing in vivo anatomical information allows determination of fiber connections which leads to brain mapping. The success of DTMRI is very ... -
Göz hareketlerine dayalı beyin bilgisayar arayüzü tasarımı
(Kırıkkale Üniversitesi, 2020)Modern teknoloji ile birlikte insanların göz hareketlerini inceleyerek uyaranlara karşı vermiş oldukları tepkiler takip edilebilir hale gelmiştir. Bu takip yöntemlerden biri de Göz İzleme (Eye-Tracking) tekniğidir. Bu ... -
Gözbebeği hareketleri temelli duygu durumu sınıflandırılması
(Gazi Üniversitesi, 2020)İnsanlardaki duygu durumu otonom sinir sistemi tarafından kontrol edilmektedir. Bu sebeple, olumlu veya olumsuz bir uyaran ile karşılaştığında otonom sinir sistemi çok kısa bir süre içerisinde, uyaran çeşidinin bireyde ... -
Identification of nucleotide patterns in meconium microbiota to improve the management of meconium aspiration syndrome in clinical practice
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2020)For many years, airways, lungs and meconium, which is a thick green substance and accumulates in the baby’s intestines during pregnancy, have been assumed to be sterile. However, this assumption has been revised by the ... -
Secondary structure dependence of amyloid-beta(1-40) on simulation techniques and force field parameters
(Wiley, 2021)Our recent studies revealed that none of the selected widely used force field parameters and molecular dynamics simulation techniques yield structural properties for the intrinsically disordered alpha-synuclein that are ... -
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation
(Wiley, 2021)ProA is a secreted zinc metalloprotease of Legionella pneumophila causing lung damage in animal models of Legionnaires' disease. Here we demonstrate that ProA promotes infection of human lung tissue explants (HLTEs) and ... -
Revisiting cu(II) bound amyloid-?40 and amyloid-?42 peptides: varying coordination chemistries
(Turkish Chemical Society, 2018)Metal ions and intrinsically disordered peptides amyloid-?40 and amyloid-?42 are at the center of Alzheimer´s disease pathology. Divalent copper ion binds to amyloid-?40 and amyloid-?42 peptides with varying coordination ... -
Current challenges and limitations in the studies of intrinsically disordered proteins in neurodegenerative diseases by computer simulations
(Bentham Science Publishers, 2020)Experiments face challenges in the analysis of intrinsically disordered proteins in solution due to fast conformational changes and enhanced aggregation propensity. Computational studies complement experiments, being widely ... -
Novel cycloheximide derivatives targeting the moonlighting protein Mip exhibit specific antimicrobial activity against Legionella pneumophila
(Frontiers Media Sa, 2015)Macrophage infectivity potentiator (Mip) and Mip-like proteins are virulence factors in a wide range of pathogens including Legionella pneumophila. These proteins belong to the FK506 binding protein (FKBP) family of ... -
Peptidylprolyl cis-trans isomerases of Legionella pneumophila: virulence, moonlighting and novel therapeutic targets
(Portland Press Ltd, 2014)Legionella pneumophila, typically a parasite of free-living protozoa, can also replicate in human alveolar macrophages and lung epithelial cells causing Legionnaires' disease in humans, a severe atypical pneumonia. The ...