Ara
Toplam kayıt 10, listelenen: 1-10
Molekularer abdruck oder selektion bei der erzeugung biomimetischer specifyer
(Springer, 2023)
Zum Ersatz oder auch zur Ergänzung von Antikörpern für niedermolekulare Substanzen wie Antibiotika, Umweltgifte und Pharmaka, aber auch für Proteinbiomarker, Viren und Mikroorganismen in Trennungstechniken, Diagnostik und ...
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)
Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ...
Molecular LEGO by domain-imprinting of cytochrome P450 BM3
(Elsevier Science Bv, 2018)
Hypothesis: Electrosynthesis of the MIP nano-film after binding of the separated domains or holocytochrome BM3 via an engineered anchor should result in domain-specific cavities in the polymer layer. Experiments: Both the ...
Electrochemical MIP-sensors for drugs
(Bentham Science Publ Ltd, 2018)
In order to replace bio-macromolecules by stable synthetic materials in separation techniques and bioanalysis biomimetic receptors and catalysts have been developed: Functional monomers are polymerized together with the ...
MIPs and aptamers for recognition of proteins in biomimetic sensing
(Mdpi, 2016)
Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides ...
Enzymes as tools in MIP-Sensors
(Mdpi, 2017)
Molecularly imprinted polymers (MIPs) have the potential to complement antibodies in bioanalysis, are more stable under harsh conditions, and are potentially cheaper to produce. However, the affinity and especially the ...
Electrosynthesized MIPs for transferrin: Plastibodies or nano-filters?
(Elsevier Advanced Technology, 2018)
Molecularly imprinted polymer (MP) nanofilrns for transferrin (Trf) have been synthesized on gold surfaces by electro-polymerizing the functional monomer scopoletin in the presence of the protein target or around pre-adsorbed ...
“Out of pocket” protein binding—A dilemma of epitope imprinted polymers revealed for human hemoglobin
(2021)
The epitope imprinting approach applies exposed peptides as templates to synthesize
Molecularly Imprinted Polymers (MIPs) for the recognition of the parent protein. While generally
the template protein binding to such ...
Peptide epitope-imprinted polymer microarrays for selective protein recognition. Application for SARSCoV-2 RBD protein
(2022)
We introduce a practically generic approach for the generation of epitope-imprinted polymer-based
microarrays for protein recognition on surface plasmon resonance imaging (SPRi) chips. The SPRi
platform allows the ...
Simple and robust: The claims of protein sensing by molecularly imprinted polymers
(2020)
A spectrum of 7562 publications on Molecularly Imprinted Polymers (MIPs) has been presented in literature
within the last ten years (Scopus, September 7, 2020). Around 10 % of the papers published on MIPs describe ...