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Toplam kayıt 28, listelenen: 1-10
Identification of nucleotide patterns in meconium microbiota to improve the management of meconium aspiration syndrome in clinical practice
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2020)
For many years, airways, lungs and meconium, which is a thick green substance and accumulates in the baby’s intestines during pregnancy, have been assumed to be sterile. However, this assumption has been revised by the ...
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)
Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ...
Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia
(American Chemical Society, 2022)
The S59L genetic mutation of the mitochondrial coiled-coil-helix-coiled-coil-helixdomain-containing protein 10 (CHCHD10) is involved in the pathogenesis of amyotrophic lateralsclerosis (ALS) and frontotemporal dementia ...
Challenges and limitations in the studies of glycoproteins: A computational chemist's perspective
(WILEY, 2021)
Experimenters face challenges and limitations while analyzing glycoproteins due to their high flexibility, stereochemistry, anisotropic effects, and hydration phenomena. Computational studies complement experiments and ...
Molecularly imprinted polymer based sensors for SARS-CoV-2: where are we now?
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)
Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome ...
Development of a larval zebrafish infection model for clostridioides difficile
(Journal Of Visualized Experiments, 2020)
Clostridioides difficile infection (CDI) is considered to be one of the most common healthcare-associated gastrointestinal infections in the United States. The innate immune response against C. difficile has been described, ...
Classification of brain electrophysiological changes in response to colour stimuli
(Springer, 2021)
In this study, the classification of ongoing brain activity occurring as a response to colour stimuli was managed and reported. Until now, the classification of the seen colour from brain electrical signals has not been ...
Current challenges and limitations in the studies of intrinsically disordered proteins in neurodegenerative diseases by computer simulations
(Bentham Science Publishers, 2020)
Experiments face challenges in the analysis of intrinsically disordered proteins in solution due to fast conformational changes and enhanced aggregation propensity. Computational studies complement experiments, being widely ...
NFI transcriptionally represses CDON and is required for SH-SY5Y cell survival
(Elsevier, 2022)
Nuclear Factor One (NFI) family of transcription factors regulate proliferation and multiple aspects of differentiation, playing analogous roles in embryonic development and various types of cancer. While all NFI family ...
Epitope region identification challenges of intrinsically disordered proteins in neurodegenerative diseases: Secondary structure dependence of alpha-synuclein on simulation techniques and force field parameters
(Wiley, 2020)
Due to fast aggregation processes of many disordered proteins in neurodegenerative diseases, it is difficult to study their epitope regions at the monomeric and oligomeric levels. Computer simulations complement experiments ...