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Toplam kayıt 42, listelenen: 1-10
Epitope region identification challenges of intrinsically disordered proteins in neurodegenerative diseases: Secondary structure dependence of alpha-synuclein on simulation techniques and force field parameters
(Wiley, 2020)
Due to fast aggregation processes of many disordered proteins in neurodegenerative diseases, it is difficult to study their epitope regions at the monomeric and oligomeric levels. Computer simulations complement experiments ...
Development of a larval zebrafish infection model for clostridioides difficile
(Journal Of Visualized Experiments, 2020)
Clostridioides difficile infection (CDI) is considered to be one of the most common healthcare-associated gastrointestinal infections in the United States. The innate immune response against C. difficile has been described, ...
Molecularly imprinted polymer based sensors for SARS-CoV-2: where are we now?
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)
Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome ...
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)
Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ...
Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia
(American Chemical Society, 2022)
The S59L genetic mutation of the mitochondrial coiled-coil-helix-coiled-coil-helixdomain-containing protein 10 (CHCHD10) is involved in the pathogenesis of amyotrophic lateralsclerosis (ALS) and frontotemporal dementia ...
Corrosion response and biocompatibility of graphene oxide (GO)–serotonin (Ser) coatings on Ti6Al7Nb and Ti29Nb13Ta4.6Zr (TNTZ) alloys fabricated by electrophoretic deposition (EPD
(Materials Today Communications, 2023)
In this study, Ti6Al7Nb and Ti29Nb13Ta4.6Zr (TNTZ) alloys coated with graphene oxide (GO) and serotonin (Ser) by electrophoretic deposition (EPD) technique were evaluated for possible usage as an orthopedic implant in terms ...
Bioreactors for tissue engineering
(Springer Cham, 2023)
Bioreactors have been widely used in various fields of biological production for many years. Their ability to provide a tightly controlled environment during the process and to allow for monitoring and intervention to the ...
Tissue regeneration processing and mimicking
(Springer Cham, 2023)
Tissue regeneration has been one of the comprehensive topics that underlie tissue engineering and has been researched over years. The main aim in tissue engineering is to create a tissue microenvironment produced from ...
Current challenges and limitations in the studies of intrinsically disordered proteins in neurodegenerative diseases by computer simulations
(Bentham Science Publishers, 2020)
Experiments face challenges in the analysis of intrinsically disordered proteins in solution due to fast conformational changes and enhanced aggregation propensity. Computational studies complement experiments, being widely ...
Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation
(Wiley, 2021)
ProA is a secreted zinc metalloprotease of Legionella pneumophila causing lung damage in animal models of Legionnaires' disease. Here we demonstrate that ProA promotes infection of human lung tissue explants (HLTEs) and ...