Başlık için Moleküler Biyoteknoloji listeleme
Toplam kayıt 83, listelenen: 37-56
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Generating simulated DT-MRI dataset
(IGI Global, 2008)Diffusion tensor magnetic resonance imaging (DTMRI), also known as diffusion tensor imaging (DTI), needs post processing by adequate image analysis and visualization tools. White matter tractography using DTI is becoming ... -
Göz hareketlerine dayalı beyin bilgisayar arayüzü tasarımı
(Kırıkkale Üniversitesi, 2020)Modern teknoloji ile birlikte insanların göz hareketlerini inceleyerek uyaranlara karşı vermiş oldukları tepkiler takip edilebilir hale gelmiştir. Bu takip yöntemlerden biri de Göz İzleme (Eye-Tracking) tekniğidir. Bu ... -
Gözbebeği hareketleri temelli duygu durumu sınıflandırılması
(Gazi Üniversitesi, 2020)İnsanlardaki duygu durumu otonom sinir sistemi tarafından kontrol edilmektedir. Bu sebeple, olumlu veya olumsuz bir uyaran ile karşılaştığında otonom sinir sistemi çok kısa bir süre içerisinde, uyaran çeşidinin bireyde ... -
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ... -
How reliable is the electrochemical readout of MIP sensors?
(Sensors,, 2020)Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by ... -
Identification of food/nonfood visual stimuli from event-related brain potentials
(Hindawi Publishing Corporation, 2021)Although food consumption is one of the most basic human behaviors, the factors underlying nutritional preferences are not yet clear. The use of classification algorithms can clarify the understanding of these factors. ... -
Identification of nucleotide patterns in meconium microbiota to improve the management of meconium aspiration syndrome in clinical practice
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2020)For many years, airways, lungs and meconium, which is a thick green substance and accumulates in the baby’s intestines during pregnancy, have been assumed to be sterile. However, this assumption has been revised by the ... -
The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10
(2023)The mitochondria are responsible for producing energy within the cell, and in mitochondrial myop-athy, there is a defect in the energy production process. The CHCHD10 gene codes for a protein calledcoiled-coil-helix-coil ... -
Improvement of design of a surgical interface using an eye tracking device
(Springer Nature, 2014)Background: Surgical interfaces are used for helping surgeons in interpretation and quantification of the patient information, and for the presentation of an integrated workflow where all available data are combined to ... -
Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice
(2023)FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient ... -
Insights in electrosynthesis, target binding, and stability of peptide-imprinted polymer nanofilms
(2021)Molecularly imprinted polymer (MIP) nanofilms have been successfully implemented for the recognition of different target molecules: however, the underlying mechanistic details remained vague. This paper provides new ... -
Insights into the molecular mechanisms of Alzheimer's and Parkinson's diseases with molecular simulations: understanding the roles of artificial and pathological missense mutations in intrinsically disordered proteins related to pathology
(Mdpi, 2018)Amyloid-beta and alpha-synuclein are intrinsically disordered proteins (IDPs), which are at the center of Alzheimer's and Parkinson's disease pathologies, respectively. These IDPs are extremely flexible and do not adopt ... -
Insights into the structural properties of SARS-CoV-2 main protease
(Elsevier BV, 2022)SARS-CoV-2 is the infectious agent responsible for the coronavirus disease since 2019, which is the viral pneumonia pandemic worldwide. The structural knowledge on SARS-CoV-2 is rather limited. These limitations are ... -
Intrinsically disordered proteins and proteins with intrinsically disordered regions in neurodegenerative diseases
(Elsevier BV., 2022)Many diferent intrinsically disordered proteins and proteins with intrinsically disordered regions are associated with neurodegenerative diseases. These types of proteins including amyloid-β, tau, α-synuclein, CHCHD2, ... -
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases
(Elsevier Academic Press Inc, 2019)Amyloid-beta (A beta) and alpha-synuclein (alpha S) are two intrinsically disordered proteins (IDPs) at the centers of the pathogenesis of Alzheimer's and Parkinson's diseases, respectively. Different hypotheses have been ... -
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer’xxs and Parkinson’xxs diseases
(Academic Press, 2019)"Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update ... -
Intrinsically disordered synthetic polymers in biomedical applications
(Polymers, 2023)In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They ... -
Microbial peptidyl-prolyl cis/trans isomerases (ppIases): virulence factors and potential alternative drug targets
(Amer Soc Microbiology, 2014)Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases (PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at peptidyl bonds preceding proline ... -
MIPs and aptamers for recognition of proteins in biomimetic sensing
(Mdpi, 2016)Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides ...