Başlık için Moleküler Biyoteknoloji listeleme
Toplam kayıt 54, listelenen: 23-42
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Fiziksel performans etkisinde mental aktivitenin elektrofizyolojik bulgularının değerlendirilmesi
(Academic Platform, 2019)Bu çalışmada, zihinsel işyükü paradigmasının yorgunluk ile ilintisine yönelik elektrofizyolojik ölçüm sonuçları iki farklı grup üzerinden incelenmiştir. Ayrık grup olarak, sporcular ve sedanterler ele alınmış olup, bu ... -
FKBPs in bacterial infections
(Elsevier Science Bv, 2015)Background: FK506-binding proteins (FKBPs) contain a domain with peptidyl-prolyl-cis/trans-isomerase (PPlase) activity and bind the immunosuppressive drugs FK506 and rapamycin. FKBPs belong to the immunophilin family and ... -
Generating simulated DT-MRI dataset
(IGI Global, 2008)Diffusion tensor magnetic resonance imaging (DTMRI), also known as diffusion tensor imaging (DTI), needs post processing by adequate image analysis and visualization tools. White matter tractography using DTI is becoming ... -
Göz hareketlerine dayalı beyin bilgisayar arayüzü tasarımı
(Kırıkkale Üniversitesi, 2020)Modern teknoloji ile birlikte insanların göz hareketlerini inceleyerek uyaranlara karşı vermiş oldukları tepkiler takip edilebilir hale gelmiştir. Bu takip yöntemlerden biri de Göz İzleme (Eye-Tracking) tekniğidir. Bu ... -
Gözbebeği hareketleri temelli duygu durumu sınıflandırılması
(Gazi Üniversitesi, 2020)İnsanlardaki duygu durumu otonom sinir sistemi tarafından kontrol edilmektedir. Bu sebeple, olumlu veya olumsuz bir uyaran ile karşılaştığında otonom sinir sistemi çok kısa bir süre içerisinde, uyaran çeşidinin bireyde ... -
How an ACE2 mimicking epitope-MIP nanofilm recognizes template-related peptides and the receptor binding domain of SARS-CoV-2
(Royal Society of Chemistry, 2022)Here we aim to gain a mechanistic understanding of the formation of epitope-imprinted polymer nanofilms using a non-terminal peptide sequence, i.e. the peptide GFNCYFP (G485 to P491) of the SARS-CoV-2 receptor binding ... -
Identification of food/nonfood visual stimuli from event-related brain potentials
(Hindawi Publishing Corporation, 2021)Although food consumption is one of the most basic human behaviors, the factors underlying nutritional preferences are not yet clear. The use of classification algorithms can clarify the understanding of these factors. ... -
Identification of nucleotide patterns in meconium microbiota to improve the management of meconium aspiration syndrome in clinical practice
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2020)For many years, airways, lungs and meconium, which is a thick green substance and accumulates in the baby’s intestines during pregnancy, have been assumed to be sterile. However, this assumption has been revised by the ... -
Improvement of design of a surgical interface using an eye tracking device
(Springer Nature, 2014)Background: Surgical interfaces are used for helping surgeons in interpretation and quantification of the patient information, and for the presentation of an integrated workflow where all available data are combined to ... -
Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice
(2023)FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient ... -
Insights into the molecular mechanisms of Alzheimer's and Parkinson's diseases with molecular simulations: understanding the roles of artificial and pathological missense mutations in intrinsically disordered proteins related to pathology
(Mdpi, 2018)Amyloid-beta and alpha-synuclein are intrinsically disordered proteins (IDPs), which are at the center of Alzheimer's and Parkinson's disease pathologies, respectively. These IDPs are extremely flexible and do not adopt ... -
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases
(Elsevier Academic Press Inc, 2019)Amyloid-beta (A beta) and alpha-synuclein (alpha S) are two intrinsically disordered proteins (IDPs) at the centers of the pathogenesis of Alzheimer's and Parkinson's diseases, respectively. Different hypotheses have been ... -
Microbial peptidyl-prolyl cis/trans isomerases (ppIases): virulence factors and potential alternative drug targets
(Amer Soc Microbiology, 2014)Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases (PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at peptidyl bonds preceding proline ... -
MIPs and aptamers for recognition of proteins in biomimetic sensing
(Mdpi, 2016)Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides ... -
Molecular LEGO by domain-imprinting of cytochrome P450 BM3
(Elsevier Science Bv, 2018)Hypothesis: Electrosynthesis of the MIP nano-film after binding of the separated domains or holocytochrome BM3 via an engineered anchor should result in domain-specific cavities in the polymer layer. Experiments: Both the ... -
Molecularly imprinted polymer based sensors for SARS-CoV-2: where are we now?
(MDPI-Multidisciplinary Digital Publishing Institute, 2022)Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome ... -
Molekularer abdruck oder selektion bei der erzeugung biomimetischer specifyer
(Springer, 2023)Zum Ersatz oder auch zur Ergänzung von Antikörpern für niedermolekulare Substanzen wie Antibiotika, Umweltgifte und Pharmaka, aber auch für Proteinbiomarker, Viren und Mikroorganismen in Trennungstechniken, Diagnostik und ... -
NFI transcriptionally represses CDON and is required for SH-SY5Y cell survival
(Elsevier, 2022)Nuclear Factor One (NFI) family of transcription factors regulate proliferation and multiple aspects of differentiation, playing analogous roles in embryonic development and various types of cancer. While all NFI family ... -
Novel cycloheximide derivatives targeting the moonlighting protein Mip exhibit specific antimicrobial activity against Legionella pneumophila
(Frontiers Media Sa, 2015)Macrophage infectivity potentiator (Mip) and Mip-like proteins are virulence factors in a wide range of pathogens including Legionella pneumophila. These proteins belong to the FK506 binding protein (FKBP) family of ... -
Novel therapeutic strategies for Clostridium difficile infections
(Taylor & Francis Ltd, 2016)Introduction: In recent years, Clostridium difficile has become the primary cause of antibiotic-associated diarrhea and pseudomembranous colitis, resulting in long and complicated hospital stays that represent a serious ...
