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Toplam kayıt 260, listelenen: 211-220
BMP-2 and BMP-9 binding specificities with ALK-3 in aqueous solution with dynamics
(Elsevier Science Inc, 2017)
Signal ligands of the transforming growth factor-beta (TGF-beta) superfamily include the bone morphogenetic proteins (BMPs). BMPs bind to type I and type II serine-threonine kinase receptors and trigger the transphosphorylation ...
Using support vector machine for the prediction of unpaid credit card debts
(Springer Verlag, 2020)
Customer behavior prediction is gaining more importance in the banking sector like in any other sector recently. This study aims to propose a model to predict whether credit card users will pay their debts or not. Using ...
Current challenges and limitations in the studies of intrinsically disordered proteins in neurodegenerative diseases by computer simulations
(Bentham Science Publishers, 2020)
Experiments face challenges in the analysis of intrinsically disordered proteins in solution due to fast conformational changes and enhanced aggregation propensity. Computational studies complement experiments, being widely ...
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases
(Elsevier Academic Press Inc, 2019)
Amyloid-beta (A beta) and alpha-synuclein (alpha S) are two intrinsically disordered proteins (IDPs) at the centers of the pathogenesis of Alzheimer's and Parkinson's diseases, respectively. Different hypotheses have been ...
Transition metal Ion interactions with disordered Amyloid-beta Peptides in the pathogenesis of Alzheimer's disease: insights from computational chemistry studies
(Amer Chemical Soc, 2019)
Monomers and oligomers of the amyloid-beta peptide aggregate to form the fibrils found in the brains of Alzheimer's disease patients. These monomers and oligomers are largely disordered and can interact with transition ...
Revisiting cu(II) bound amyloid-?40 and amyloid-?42 peptides: varying coordination chemistries
(Turkish Chemical Society, 2018)
Metal ions and intrinsically disordered peptides amyloid-?40 and amyloid-?42 are at the center of Alzheimer´s disease pathology. Divalent copper ion binds to amyloid-?40 and amyloid-?42 peptides with varying coordination ...
Tyrosine regulates beta-sheet structure formation in amyloid-beta(42): a new clustering algorithm for disordered proteins
(Amer Chemical Soc, 2017)
Our recent studies show that the single Tyr residue in the sequence of amyloid-beta(42) (A beta(42)) is reactive toward various ligands, including metals and adenosine trisphospate (see: Coskuner, O. J. Biol. Inorg. Chem. ...
Predicting the success of ensemble algorithms in the banking sector
(Igi Global, 2019)
The banking sector, like other service sector, improves in accordance with the customer's needs. Therefore, to know the needs of customers and to predict customer behaviors are very important for competition in the banking ...
Molecular simulations of IDPs: From ensemble generation to IDP interactions leading to disorder-to-order transitions
(Academic Press Inc Elsevier Science, 2021)
Intrinsically disordered proteins (IDPs) lack a well-defined three-dimensional structure but do exhibit some dynamical and structural ordering. The structural plasticity of IDPs indicates that entropy-driven motions are ...
Development of a nonwetting coating for packaging substrate surfaces using a novel and easy to implement method
(Walter de Gruyter, 2021)
This study is about preparing different paper substrates with chemically stable hydrophobic and superhydrophobic surface coatings through spraying a mixture of poly(dimethylsiloxane) (PDMS) and inorganic particles. The ...