Now showing items 1-10 of 10
Novel therapeutic strategies for Clostridium difficile infections
(Taylor & Francis Ltd, 2016)
Introduction: In recent years, Clostridium difficile has become the primary cause of antibiotic-associated diarrhea and pseudomembranous colitis, resulting in long and complicated hospital stays that represent a serious ...
FKBPs in bacterial infections
(Elsevier Science Bv, 2015)
Background: FK506-binding proteins (FKBPs) contain a domain with peptidyl-prolyl-cis/trans-isomerase (PPlase) activity and bind the immunosuppressive drugs FK506 and rapamycin. FKBPs belong to the immunophilin family and ...
Electrochemical MIP-sensors for drugs
(Bentham Science Publ Ltd, 2018)
In order to replace bio-macromolecules by stable synthetic materials in separation techniques and bioanalysis biomimetic receptors and catalysts have been developed: Functional monomers are polymerized together with the ...
Global climate change, environment and energy: global challenges and opportunities to global stability
(Seta Foundation, 2017)
Influence of urban built environment on traffic accidents: the case of Eskisehir (Turkey)
This paper explores effects of urban the built environment on traffic accidents in the context of a developing country. The basic objective of this study is to use simple and practical models to analyze traffic accidents, ...
China's Asian dream: quiet empire building along the New Silk Road
(Seta Foundation, 2018)
Numerical and experimental analysis of a heat-pipe-embedded printed circuit board for solid state lighting applications
(Taylor & Francis Inc, 2019)
Thermal management is one of the main issues for electronics cooling especially for tightly packaged PCBs that experience local heat generation. Thus, theoretical and experimental investigations have been conducted to ...
Intrinsically disordered proteins in various hypotheses on the pathogenesis of Alzheimer's and Parkinson's diseases
(Elsevier Academic Press Inc, 2019)
Amyloid-beta (A beta) and alpha-synuclein (alpha S) are two intrinsically disordered proteins (IDPs) at the centers of the pathogenesis of Alzheimer's and Parkinson's diseases, respectively. Different hypotheses have been ...
Transition metal Ion interactions with disordered Amyloid-beta Peptides in the pathogenesis of Alzheimer's disease: insights from computational chemistry studies
(Amer Chemical Soc, 2019)
Monomers and oligomers of the amyloid-beta peptide aggregate to form the fibrils found in the brains of Alzheimer's disease patients. These monomers and oligomers are largely disordered and can interact with transition ...
Janus interface materials: a critical review and comparative study
(Amer Chemical Soc, 2020)
In recent years, Janus interface materials with wettability contrast have attracted remarkable attention because of their beneficial properties and versatile potential applications in materials science including transport, ...